GMCALab solves Blind Source Separation (BSS) problems from multichannel/multispectral/hyperspectral data. In essence, multichannel data provide different observations of the same physical phenomena (e.g. multiple wavelengths), which are modeled as a linear combination of unknown elementary components or sources. Written as a set of Matlab toolboxes, it provides a generic framework that can be extended to tackle different matrix factorization problems.