ScamPy "paints" an observed population of cosmological objects on top of the DM-halo/subhalo hierarchy obtained from DM-only simulations. The method combines the Halo Occupation Distribution (HOD) method with sub-halo abundance matching (SHAM); the two processes together are dubbed Sub-halo clustering and abundance matching (SCAM). The procedure requires applying the two methods in sequence; by applying the HOD scheme, the host sub-haloes are selected, and the SHAM algorithm associates an observable property of choice to each sub-halo. The provided python interface allows users to load and populate DM halos and sub-halos obtained by FoF and SUBFIND algorithms applied to DM snapshots at any redshift. The software is highly-optimized and flexible.