MOCPy creates, parses, and manipulates Multi-Order Coverage (MOC) maps. MOC is an IVOA standard enabling description of arbitrary sky regions. Based on the HEALPix sky tessellation, it maps regions on the sky into hierarchically grouped predefined cells. MOCPy provides the MOC, TimeMOC, FrequencyMOC, and STMOC classes to handle the manipulation of spatial, temporal, frequency, and space-time MOCs respectively.