PyAutoFit supports advanced statistical methods such as massively parallel non-linear search grid-searches, chaining together model-fits and sensitivity mapping. It is a Python-based probabilistic programming language which composes and fits models using a range of Bayesian inference libraries, such as emcee (ascl:1303.002) and dynesty (ascl:1809.013). It performs model composition and customization, outputting results, model-specific visualization and posterior analysis. Built for big-data analysis, results are output as a database which can be loaded after model-fitting is complete.