The Python package sympy2c allows creation and compilation of fast C/C++ based extension modules from symbolic representations. It can create fast code for the solution of high dimensional ODEs, or numerical evaluation of integrals where sympy fails to compute an anti-​derivative. Based on the symbolic formulation of a stiff ODE, sympy2c analyzes sparsity patterns in the Jacobian matrix of the ODE, and generates loop-​less fast code by unrolling loops in the internally used LU factorization algorithm and by avoiding unnecessary computations involving known zeros.