JOFILUREN analyzes and de-noises scientific data and is useful for studying and reducing the physical effects of particle noise in particle-mesh computer simulations. It uses wavelets, which can efficiently remove noise from cosmological, galaxy and plasma N-body simulations. Written in Fortran, the code is portable and can be included in grid-based N-body codes. JOFILUREN can also be applied for removing noise from standard data, such as signals and images.